Informace o publikaci

Reference values of cardio-ankle vascular index in a random sample of a white population

Autoři	WOHLFAHRT P. CIFKOVA R. MOVSISYAN N. KUNZOVÁ Šárka LEŠOVSKÝ Jiří HOMOLKA M. SOŠKA Vladimír DOBŠÁK Petr LOPEZ-JIMENEZ F. SOCHOR Ondřej
Rok publikování	2017
Druh	Článek v odborném periodiku
Časopis / Zdroj	journal of Hypertension
Fakulta / Pracoviště MU	Lékařská fakulta
Citace
Doi	http://dx.doi.org/10.1097/HJH.0000000000001437
Obor	Kardiovaskulární nemoci včetně kardiochirurgie
Klíčová slova	arterial stiffness; cardio-ankle vascular index; reference values; white population
Popis	Objectives: Cardio-ankle vascular index (CAVI), a parameter of arterial stiffness, has been increasingly used for cardiovascular risk estimation. Currently used CAVI reference values are derived from the Japanese population. It is not clear whether the same reference values can be used in the white population. The aim of the present study was to describe cardiovascular risk factors influencing CAVI and to establish CAVI reference values. Methods: A total of 2160 individuals randomly selected from the Brno city population aged 25-65 years were examined. Of these, 1347 patients were free from cardiovascular disease, nondiabetic and untreated by antihypertensive or lipid-lowering drugs, forming the reference value population. CAVI was measured using the VaSera VS-1000 device (Fukuda Denshi, Tokyo, Japan). Results: At each blood pressure (BP) level, there was a quadratic association between CAVI and age, except for a linear association in the optimal BP group. Although there was no association between BP and CAVI in younger patients, there was a linear association between CAVI and BP after 40 years of age. Reference values by age and sex were established. In each age group, except for the male 60-65-year group, reference values in our population were lower than in the Japanese one with the difference ranging from -0.29 to 0.21 for men, and from -0.38 to -0.03 for women. Conclusion: This is the first study providing CAVI reference values in a random sample of the white population. Our results suggest that the currently used values slightly overestimate CAVI in younger white, possibly underestimating cardiovascular risk.