Informace o publikaci
Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates
Autoři | |
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Rok publikování | 2017 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Blood Cells, Molecules and Diseases |
Citace | |
Doi | http://dx.doi.org/10.3390/molecules22071199 |
Klíčová slova | alkylcarbamates; hydroxynaphthalene-carboxamides; PET inhibition; spinach chloroplasts; structure-activity relationships |
Popis | Eight 1-[(2-chlorophenyl)carbamoyl]naphthalen-2-yl alkylcarbamates and eight 1-[(2-nitrophenyl)carbamoyl]naphthalen-2-yl alkylcarbamates were tested for their activity related to the inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. The PET-inhibiting activity of the compounds was relatively low; the corresponding IC50 values ranged from 0.05 to 0.664 mmol/L; and the highest activity within the series of compounds was observed for 1-[(2-chlorophenyl)-carbamoyl] naphthalen-2-yl propylcarbamate. It has been proven that the compounds are PET-inhibitors in photosystem II. Despite rather low PET-inhibiting activities, primary structure-activity trends can be discussed. |