Informace o publikaci

Association of the CD14 -260C/T polymorphism with plaque-induced gingivitis depends on the presence of Porphyromonas gingivalis

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BARTOŠOVÁ Michaela BOŘILOVÁ LINHARTOVÁ Petra MUSILOVÁ Kristína BROUKAL Zdeněk KUKLETOVÁ Martina KUKLA Lubomír IZAKOVIČOVÁ HOLLÁ Lydie

Rok publikování 2021
Druh Článek v odborném periodiku
Časopis / Zdroj International Journal of Paediatric Dentistry
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://onlinelibrary.wiley.com/doi/abs/10.1111/ipd.12847
Doi http://dx.doi.org/10.1111/ipd.12847
Klíčová slova bacteria; CD14; gingivitis; polymorphism
Popis This study investigated the association between the functional polymorphism in the CD14 gene and the dental plaque microbiota in children with gingivitis.Gingivitis was detected in 64.2% of boys, but only in 35.8% of girls (P < .001). Children with gingivitis had a significantly higher occurrence of dental caries (P < .001). No significant differences in the CD14 -260C/T allele and genotype distribution among individuals with or without gingivitis in the whole cohort were found. Children with gingivitis and P gingivalis, however, were significantly more frequent carriers of the CT and TT genotypes than children with gingivitis without P gingivalis or healthy controls (P < .05).
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