Informace o publikaci

Approaches for in vitro culture of granulosa cells and ovarian follicles

Autoři

ZGÓRECKA Wiktoria JEŠETA Michal PROCHAZKA Radek AMORIM Christiani A. KRAJNIK Kornelia MOZDZIAK Paul PIEŃSKOWSKI Wojciech SKOWROŃSKI Mariusz T. KRANC Wiesława

Rok publikování 2022
Druh Článek v odborném periodiku
Časopis / Zdroj Medical Journal of Cell Biology
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://sciendo.com/es/article/10.2478/acb-2022-0006
Doi http://dx.doi.org/10.2478/acb-2022-0006
Klíčová slova granulosa cells (GCs); cumulus-oocyte complexes (COC); ovarian follicle; ovarian follicle; in vi-tro culture systems
Popis The in vitro culture of ovarian follicles or cumulus-oocyte complexes (COC) is used to study the factors that regulate follicular development and may have potential use in artificial reproductive technology (ART). Be-fore ovulation, the follicle is formed by oocyte and cell populations known as granulosa cells (GCs). These cells build the internal and external mass of the follicular wall. Oocyte growth and proliferation of the sur-rounding cells depend on the gap junctions between the oocyte and the GCs. Maintenance of the optimal in vitro culture system allowing for preservation of follicle architecture and granulosa-oocyte interaction may be critical for success in vitro maturation of follicles. Recently many studies have focused on a culture of GCs, which have important functions related to steroidogenesis. Granulosa cells maintained in in vitro conditions exhibit stem cell properties making it important to consider in vitro culture (IVC) methods of the GC population.

Používáte starou verzi internetového prohlížeče. Doporučujeme aktualizovat Váš prohlížeč na nejnovější verzi.

Další info