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Distribution patterns of LTR retrotransposons in monocentric and holocentric chromosomes

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PANDA Klára

Rok publikování 2025
Druh Konferenční abstrakty
Fakulta / Pracoviště MU

Přírodovědecká fakulta

Citace
Popis Transposable elements can constitute a significant fraction of eukaryotic genomes, with long terminal repeat retrotransposons (LTR-RTs) being particularly prevalent in plants. In monocentric chromosomes (with localized centromere), recombination rates vary along chromosome, with suppression in pericentromeric and other heterochromatic regions. LTR-RTs may “hide” in these recombination cold regions. In contrast, holocentric chromosomes (lacking a single localized centromere) exhibit a more uniform chromatin structure without evident euchromatic or heterochromatic clusters. Therefore, recombination may be more or less homogeneously distributed along holocentric chromosomes, making it difficult for LTR-RTs to evade removal. We hypothesize that this uniform recombination facilitates a more even removal of LTR-RTs in holocentric chromosomes compared to monocentric chromosomes.
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