Informace o publikaci

Design and validation of a mixed reality workflow for structural cardiac procedures in interventional cardiology

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HECKO Jan PRECEK Daniel JANUSKA Jaroslav HUDEC Miroslav BARNOVA Katerina PALICKOVA-MIKOLASOVA Martina PEKAŘ Matej CHOVANCIK Jan SKNOURIL Libor JIRAVSKY Otakar

Rok publikování 2025
Druh Článek v odborném periodiku
Časopis / Zdroj FRONTIERS IN VIRTUAL REALITY
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://www.frontiersin.org/journals/virtual-reality/articles/10.3389/frvir.2025.1690439/full
Doi https://doi.org/10.3389/frvir.2025.1690439
Klíčová slova mixed reality; HoloLens 2; interventional cardiology; volume rendering; usability validation; workflow integration; multi-user collaboration; performance metrics
Popis Background Mixed reality (MR) technologies, such as those integrating Unity and Microsoft HoloLens 2, hold promises for enhancing non-coronary interventions in interventional cardiology by providing real-time 3D visualizations, multi-user collaboration, and gesture-based interactions. However, barriers to clinical adoption include insufficient validation of performance, usability, and workflow integration, aligning with the Research Topic on transforming medicine through extended reality (XR) via robust technologies, education, and ethical considerations. This study addresses these gaps by developing and rigorously evaluating an MR system for procedures like transcatheter valve replacements and atrial septal defect repairs.Methods The system was built using Unity with modifications to the UnityVolumeRendering plugin for Digital Imaging and Communications in Medicine (DICOM) data processing and volume rendering, Mixed Reality Toolkit (MRTK) for user interactions, and Photon Unity Networking (PUN2) for multi-user synchronization. Validation involved technical performance metrics (e.g., frame rate, latency), measured via Unity Profiler and Wireshark during stress tests. Usability was assessed using the System Usability Scale (SUS) and NASA Task Load Index (NASA-TLX), as well as through task-based trials. Workflow integration was evaluated in a simulated cath-lab setting with six cardiologists, focusing on calibration times and responses to a custom questionnaire. Statistical analysis included means +/- standard deviation (SD) and 95% confidence intervals.Results Technical benchmarks showed frame rates of 59.6 +/- 0.7 fps for medium datasets, local latency of 14.3 +/- 0.5 ms (95% CI: 14.1-14.5 ms), and multi-user latency of 26.9 +/- 12.3 ms (95% CI: 23.3-30.5 ms), with 91% gesture recognition accuracy. Usability yielded a SUS score of 77.5 +/- 3.8 and NASA-TLX of 37 +/- 7, with task completion times under 60 s. Workflow metrics indicated 38 s calibration and high communication benefits (4.5 +/- 0.2 on a 1-5 scale).Conclusion This validated MR solution demonstrates feasibility for precise, collaborative cardiac interventions, paving the way for broader XR adoption in medicine while addressing educational and ethical integration challenges.

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