Informace o publikaci
Influence of cannabinoid receptor CB1 agonist ACPA and CB2 agonist JWH 015 on mouse leukocyte phagocytosis
| Autoři | |
|---|---|
| Rok publikování | 2003 |
| Druh | Článek ve sborníku |
| Konference | Psychiatrie, Supplementum 1, 2003 |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Farmakologie a lékárnická chemie |
| Klíčová slova | cannabinoids; ACPA; JWH 015; leukocyte phagocytosis; chemiluminescence |
| Popis | The cannabinoids are involved in regulation of immune function. This action can be mediated either through cannabinoid receptors which subtypes CB1 and CB2 have been identified on leukocytes, or by non-receptor mechanism not clearly understood yet. The present study investigated th influence of the CB1 receptor agonist ACPA and the CB2 receptor agonist JWH 015 on the cellular immune function on leukocyte phagocytosis. Phagocytic activity of mouse leukocytes was measured in chemiluminescence (CL) assay using zymosan induction of phagocytosis and luminol potentiated of CL in vitro. |
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