Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2

• Autoři: PARUCH Kamil; DWYER Michael; ALVAREZ Carmen; BROWN Courtney; CHAN Tin-Yau; DOLL Ronald; KEERTIKAR Kerry; KNUTSON Chad; MCKITTRICK Brian; RIVERA Jocelyn; ROSSMAN Randall; TUCKER Greg; FISCHMANN Thierry; HRUZA Alan; MADISON Vincent; NOMEIR Amin; WANG Yaolin; LEES Emma; PARRY David; SGAMBELLONE Nicole; SEGHEZZI Wolfgang; SCHULTZ Lesley; SHANAHAN Fran; WISWELL Derek; XU Xiaoying; ZHOU Quiao; JAMES Ray; PARADKAR Vidyadhar; PARK Haengsoon; ROKOSZ Laura; STAUFFER Tara; GUZI Timothy
• Rok publikování: 2007
• Druh: Článek v odborném periodiku
• Časopis / Zdroj: Bioorganic & Medicinal Chemistry Letters
• Fakulta / Pracoviště MU: Přírodovědecká fakulta

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• Obor: Farmakologie a lékárnická chemie
• Klíčová slova: CDK2 kinase; inibitor; cancer
• Popis: viz anotace