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Effect of sequential frontotemporal repetitive transcranial magnetic stimulation (rTMS) on schizophrenia

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PŘIKRYL Radovan USTOHAL Libor PŘIKRYLOVÁ KUČEROVÁ Hana ČERMÁKOVÁ Iva ČEŠKOVÁ Eva

Rok publikování 2010
Druh Článek v odborném periodiku
Časopis / Zdroj Activitas Nervosa Superior Rediviva
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Obor Psychiatrie, sexuologie
Klíčová slova CSP; frontotemporal; rTMS; schizophrenia; stimulation
Popis Modulation of the symptoms of schizophrenia, with the exception of the auditory hallucinations, by rTMS requires a new stimulation paradigm. Unipolar, left-sided, sequential fronto-temporal rTMS produce a significant reduction in all schizophrenia symptoms, especially the positive ones. A reduction in schizophrenic psychopathology was associated with prolongation of the CSP period, which can be assessed as an objective marker of reactivity. Since dual stimulation was well tolerated, it represents an alternative stimulation paradigm for treatment of schizophrenia. Complete verification will require a larger patient population sample, and preferably a double-blind study protocol. Unipolar, left side, sequential fronto-temporal rTMS caused alleviation of the symptoms of schizophrenia and was well tolerated. Therefore it may represent a new alternative therapy for schizophrenic patients.
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