Informace o publikaci
1q21 amplification with additional genetic abnormalities but not isolated 1q21 gain is a negative prognostic factor in newly diagnosed patients with multiple myeloma treated with thalidomide-based regimens
| Autoři | |
|---|---|
| Rok publikování | 2012 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Leukemia & lymphoma |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | http://informahealthcare.com/doi/abs/10.3109/10428194.2012.684349 |
| Doi | http://dx.doi.org/10.3109/10428194.2012.684349 |
| Obor | Onkologie a hematologie |
| Klíčová slova | In-Situ Hybridization; Expression; Chromosome-1; Survival; Model |
| Přiložené soubory | |
| Popis | In this study we assessed the prognostic value of amp(1q21) alone and in combination with del(17p13), del(13q14) and t(4,14)(p16;q32) detected by fl uorescence in situ hybridization(FISH) in newly diagnosed patients with MM treated with thalidomide-based induction regimens. Th e primary endpoints were response rate after fi rst-line therapy, PFS and OS. |