Informace o publikaci

Effect of spontaneous activity on stimulus detection in a simple neuronal model

Autoři

LEVÁKOVÁ Marie

Rok publikování 2016
Druh Článek v odborném periodiku
Časopis / Zdroj Mathematical Biosciences and Engineering
Fakulta / Pracoviště MU

Přírodovědecká fakulta

Citace
www https://aimsciences.org/journals/displayArticlesnew.jsp?paperID=12217
Doi http://dx.doi.org/10.3934/mbe.2016007
Obor Aplikovaná statistika, operační výzkum
Klíčová slova Fisher information; latency coding; spontaneous activity; renewal process; neuroscience
Popis It is studied what level of a continuous-valued signal is optimally estimable on the basis of first-spike latency neuronal data. When a spontaneous neuronal activity is present, the first spike after the stimulus onset may be caused either by the stimulus itself, or it may be a result of the prevailing spontaneous activity. Under certain regularity conditions, Fisher information is the inverse of the variance of the best estimator. It can be considered as a function of the signal intensity and then indicates accuracy of the estimation for each signal level. The Fisher information is normalized with respect to the time needed to obtain an observation. The accuracy of signal level estimation is investigated in basic discharge patterns modelled by a Poisson and a renewal process and the impact of the complex interaction between spontaneous activity and a delay of the response is shown.
Související projekty:

Používáte starou verzi internetového prohlížeče. Doporučujeme aktualizovat Váš prohlížeč na nejnovější verzi.

Další info