Informace o publikaci
ARE INCREASED URIC ACID LEVELS IN PREGNANCY COMPLICATED BY GESTATIONAL DIABETES MELLITUS LINKED TO IMPAIRED GLUCOSE TOLERANCE?
|Popis||Increased uric acid (UA) levels were associated with obesity, hypertension and insulin resistance. Moreover serum UA levels show substantial genetic component. We hypothesize that increased UA in pregnancy can serve as a marker of more severe insulin resistance leading to high-risk gestational diabetes mellitus (GDM) and, hypothetically, to diabetes development soon after delivery. We therefore assessed UA levels during pregnancy and postpartum in a group of women with GDM and healthy pregnant counterparts and associated them with a severity of carbohydrate abnormalities in the 2nd trimester and other adverse outcomes.|