Informace o publikaci

Identification of novel chronic lymphocytic leukemia subtypes using pathway mutation scores and consensus clustering

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TAUŠ Petr PLEVOVÁ Karla DARZENTAS Nikos PÁL Karol POSPÍŠILOVÁ Šárka

Druh Konferenční abstrakty
Fakulta / Pracoviště MU

Středoevropský technologický institut

Citace
Popis Chronic lymphocytic leukemia (CLL) is the most common adult leukemia with variable clinical course underlain by striking genetic heterogeneity. CLL features a handful of putative driver genes and, more interestingly, a large number of non-recurrently mutated genes with elusive clinical implications. The aim of this study was to unravel the prognostic impact of pathway somatic mutation patterns in CLL.
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