SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES

• Autoři: PARUCH Kamil; CARBAIN Benoit Jean-Pierre; HAVEL Štěpán; DAMBORSKÝ Jiří; BREZOVSKÝ Jan; DANIEL Lukáš; SISÁKOVÁ Alexandra; NIKULENKOV Fedor; KREJČÍ Lumír
• Rok publikování: 2021
• Druh: Patent
• Fakulta / Pracoviště MU: Přírodovědecká fakulta
• Vydavatel: European Patent Office
• Stát vydání: Německo
• Číslo patentu: EP3556755B1
• www: https://worldwide.espacenet.com/patent/search?q=pn%3DEP3556755B1
• Popis: The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.