Informace o publikaci
Polymeric carrier for vaginal administration of antimicrobial phytotherapeutics
| Autoři | |
|---|---|
| Rok publikování | 2025 |
| Druh | Konferenční abstrakty |
| Fakulta / Pracoviště MU | |
| Citace | |
| Popis | Natural mucoadhesive polymers, such as sodium alginate, have garnered significant research attention for their beneficial properties in developing modern dosage forms, including vaginal drug delivery for infections treatment. Sodium alginate can form polymer hydrogel particles through external ionic gelation with safe cross-linking ions like Ca2+ [1]. These polymer carriers can serve as vehicles to incorporate biologically active natural substances derived from plant sources such as thymol, eugenol, and carvacrol. Their combinations may exhibit synergistic effects that hold promise in combating infectious diseases [2]. By integrating these substances into mucoadhesive polymers, we can leverage their effects when applied to mucous membranes. This study will explore the antimicrobial synergistic impact of these aforementioned phytotherapeutics against Escherichia coli (E. coli). |