Informace o publikaci
Cytotoxic effects of colicins E1 and E3 on v-myb-transformed monoblasts
Autoři | |
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Rok publikování | 2001 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Folia Biologica |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Genetika a molekulární biologie |
Klíčová slova | colicin; proliferation; cee death; v-myb; monoblasts |
Popis | Colicins show a considerable cytostatic activity. In this communication, the cytotoxic effects of colicins E1 and E3 on v-myb-transformed chicken monoblasts BM2 are presented. We detected clear reduction of the viable cell number induced by colicin E1 and E3, occuring without apparent changes in cell cycle profiles. The level of inhibition was proportional to colicin concentration. This result documents tha colicins exert their cytotoxic effects on leukemic cells. |
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