Informace o publikaci

Structural studies of benzophenanthridine alkaloid free bases by NMR spectroscopy

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SEČKÁŘOVÁ Pavlína MAREK Radek DOSTÁL Jiří DOMMISSE Roger ESMANS Eddy L.

Rok publikování 2002
Druh Článek v odborném periodiku
Časopis / Zdroj Magnetic Resonance in Chemistry
Fakulta / Pracoviště MU

Přírodovědecká fakulta

Citace
www http://www3.interscience.wiley.com/cgi-bin/abstract/88512831/START
Obor Organická chemie
Klíčová slova NMR; 1H NMR; 13C NMR; benzophenanthridine alkaloids; free base formation; GHMBC; GSQMBC; pseudobases
Popis The free bases of eight quaternary benzo[c]phenanthridine alkaloids were investigated by 1H and 13C NMR spectroscopy. The pseudobases (the 6-hydroxy-5,6-dihydro derivatives) were found to be the only products of the alkalization in DMSO-d6 solution. In less polar solvents the formation of the bimolecular aminoacetal structure is preferred. In biological systems, free bases of the alkaloids are assumed to adopt the pseudobase structure.
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