Informace o publikaci
Increased activity of superoxid dismutase in advanced stages of head and neck squamous cell carcinoma with locoregional metastases
| Autoři | |
|---|---|
| Rok publikování | 2007 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Neoplasma |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | ORL, oftalmologie, stomatologie |
| Klíčová slova | antioxidative enzymes; head and neck cancer; metastasis; oxidative stress; polymorphism; syuperoxide dismutase |
| Popis | Our results suggest that increased p-SOD at the time of the initial treatment for HNSCC is connected with a greater extent and nodal metastatic spread of the initial disease and an earlier disease relapse. Progression of diseases might be further modified by the presence of Ala/Ala genotype of the SOD2. Activity of p-SOD could thus offer diagnostic as well as prognostic value. |
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