Informace o projektu
The national infrastructure C4SYS - Centre for Systems Biology
(C4SYS)
- Kód projektu
- LM2015055
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
- Přírodovědecká fakulta
- Další fakulta/pracoviště MU
- Fakulta informatiky
- Spolupracující organizace
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Mikrobiologický ústav AV ČR, v. v. i.
Jihočeská univerzita v Českých Budějovicích
Centrum výzkumu globální změny AV ČR, v. v. i.
The national infrastructure C4SYS - Centre for Systems Biology is a priority infrastructure project on the national roadmap, and currently in its preparatory phase, building on close collaboration between the Academy of Sciences (Institute of Microbiology, Prague, Institute of Nanobiology and Structural Biology, Nove Hrady, Global Change Research Center, Brno), the University of South Bohemia, and Masaryk University, Brno. It has the ambition to concentrate the knowledge potential in the field of systems biology in the Czech Republic and to connect the diverted systems biology research at the Academy of Sciences and various universities in the Czech Republic to the european infastructure (ISBE). C4SYS will enable Czech ad European laboratories to model, conduct experiments and proceed other activities, where they cannot be done locally, but which are required for their systems biology research. This virtual platform is providing the research community resources and services for the implementation of cutting-edge research and development internationally. This is an essential point because Systems Biology requires significantly more multidisciplinary facilities and international access than are typically present in any single institute. The infrastructure was initiated in 2009 as a divison of the former Institute of Systems Biology and Ecology of the Academy of Sciences of the Czech Republic, and became part of the Czech roadmap as a promising project in the 2010 update, and a high-priority project in the 2011 update. In 2014 the above mentioned institutions signed a memorandum of understanding, that finalizes the preparatory phase and initiates the construction phase that is planned for 2015-2017.
Publikace
Počet publikací: 70
2018
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CAVER Analyst 2.0: Analysis and Visualization of Channels and Tunnels in Protein Structures and Molecular Dynamics Trajectories
Bioinformatics, rok: 2018, ročník: 34, vydání: 20, DOI
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Computer-assisted engineering of hyperstable fibroblast growth factor 2
Biotechnology and Bioengineering, rok: 2018, ročník: 115, vydání: 4, DOI
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Evolutionary Analysis As a Powerful Complement to Energy Calculations for Protein Stabilization
ACS Catalysis, rok: 2018, ročník: 8, vydání: 10, DOI
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Exploration of Enzyme Diversity by Integrating Bioinformatics with Expression Analysis and Biochemical Characterization
ACS Catalysis, rok: 2018, ročník: 8, vydání: 3, DOI
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Fully Automated Attractor Analysis of Cyanobacteria Models
22nd International Conference on System Theory, Control and Computing, rok: 2018
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Gram-scale Production of Recombinant Microbial Enzymes in Shake Flasks
FEMS Microbiology Letters, rok: 2018, ročník: 365, vydání: 2, DOI
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Haloalkane Dehalogenases From Marine Organisms
MARINE ENZYMES AND SPECIALIZED METABOLISM, PT B, rok: 2018, ročník: 605, vydání: 1, DOI
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HotSpot Wizard 3.0: web server for automated design of mutations and smart libraries based on sequence input information
Nucleic Acids Research, rok: 2018, ročník: 46, vydání: W1, DOI
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Impact of the access tunnel engineering on catalysis is strictly ligand-specific
the FEBS Journal, rok: 2018, ročník: 285/2018, vydání: 8, DOI
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Influence of circadian clocks on optimal regime of central C-N metabolism of cyanobacteria
Cyanobacteria: From Basic Science to Applications, vydání: Vyd. 1st ed., rok: 2018, počet stran: 14 s.